Thursday, October 31, 2019

The Al Qaeda Manual Essay Example | Topics and Well Written Essays - 750 words

The Al Qaeda Manual - Essay Example The manual demonstrates that Al Qaeda is more than just a religious militant terrorist group set on destroying western interests and attacking western values, it also highlights the difficult task that law enforcement is faced with in the modern war on terror. There is little doubt that the Al Qaeda manual asks its followers to be specifically anti-Western and anti-US. The manual proclaims that "Colonialism and its followers, the apostate rulers, then started to openly erect crusader centers, societies, and organizations like Masonic Lodges, Lions and Rotary clubs, and foreign schools" (Al Qaeda Manual, n.d., p.8). These are the symbols that they perceive as American. The manual further radicalizes its readers by tying these activities to religion. "The bitter situation that the nation has reached is a result of its divergence from Allah's course and his righteous law for all places and times" (Al Qaeda Manual, n.d., p.9). By casting the Western symbols as anti-Islamic they are able to exploit the centuries old religious fears and furors that have historically pitted Islam against Christianity. 1 Along with being an extremist religious organization, the manual indoctrinates the reader to the military arm of Al Qaeda. The document professes its need for illegal documents and counterfeit currency. These resources are then to be used to commit violence against the US and their interests anywhere around the world. There is no doubt about their propensity for violence when the state that their goals are "Kidnaping enemy personnel, assassinating enemy personnel as well as foreign tourists, blasting and destroying the places of amusement, the embassies and attacking vital economic centers, [and] bridges leading into and out of the cities" (Al Qaeda Manual, n.d., p.13). The manual is also quite detailed in the requirements for forged documents. It explains what type of documents are needed, how many to possess, and requires that members' documents have a picture without a beard (Al Qaeda Manual, n.d., p.23). While this non-dated document may be more difficult to implement in today 's world of heightened security, it demonstrates their organizational commitment to doing anything necessary to subvert US interests around the world. 2 There is the question as to whether or not the possession of this document could identify someone as a terrorist and subject them to arrest under the current US Law. The professing of violence against specific targets, advocating illegal activity, and the ties to an organization labeled by the State Department as a terrorist group, would place the person who posses this document at some risk of being suspected of being a terrorist. This brings into question whether I will be at risk since I have downloaded a copy to my computer and I do not have the technology to eradicate it from the disc drive. While I would like to think that justice would win out and an explanation of "used for academic purposes" would be enough, the headlines are full of the innocent people who are still in obscure prisons for terrorist activities. This could be further complicated if I was an Islamic student that was studying in America. This manual not only illustrates the depth of commitment that Al Qaeda h as to its goals, it also shows the difficulty that law enforcement has in regards to its ability to evaluate motivation, intent, and

Tuesday, October 29, 2019

Marketing Research Paper Example | Topics and Well Written Essays - 1750 words

Marketing - Research Paper Example Global challenge 1 One of the challenges that an organization is most likely to face in developing and launching its products in the international market is its management efficiency with respect to the production process. This challenge was particularly identified in the development of Hexopater. Management of the production process of a product, whether a locally marketed product or one that targets the international market, has many impacts on the quality of the product to be produced as well as the reliability in the continuous flow of the product into its market. An effective management of a production process begins with development of aims of the production as well as the features of the product, a stage that is crucial and defines the destiny of the product. Inability to develop focused goals that can yield a successful production as well as failure to identify captivating features that will attract customers therefore forms a significant challenge to product launch in the gl obal market. This is because a challenged set of development goals, coupled with poor specification may lead to poor standards that may not be acceptable for clearance across borders (Kumar and Addie, 2006). ... This is because the human resource competence level is reflected in the production process, quality and the image that consumers and even regulatory bodies develop over a product. The overall plan of the production process as well as sales initiatives also determines the extent of challenges that a product can experience in penetrating an international market. Management of the production process is therefore a significant challenge in any product development as it applied to Hexopater (Kumar and Addie, 2006). Global challenge 2 Another challenge facing development of products in global markets is the level of regulations that are instituted by different territories. Though most regulatory measures are meant to check on safety of products to be allowed from other economies, some regulatory measures are done on economic grounds. The impact however remains the same, that regulations undermines the ability to develop and market a product in the international market. An example of such r egulation is the European union’s move to regulate â€Å"tissue related products† (Dodin, 2010, p. 1). This particular regulatory initiative was meant to harmonize laws in the region and to ensure that the developments in scientific processes are monitored and regulated effectively. While the regulations ensured common application of rules in the region, it influenced original regulations in each countries in either way. It either lowered standards for the countries that were highly regulated and raised standards for countries that were poorly regulated. The greatest challenge to new product development in the region would therefore be significant in the countries that were previously less strictly regulated. A firm

Sunday, October 27, 2019

Formulation and Characterization of Microemulsion System

Formulation and Characterization of Microemulsion System Abstract Formulation of a new oil-in-water (o/w) microemulsion composed of Castor oil/Tween 80/Ethanol/Phosphate buffer for enhancing the loading capacity of an anti-inflammatory drug piroxicam has been accomplished. The pseudo-ternary phase diagram has been delineated at constant surfactant/cosurfactant ratio (1:2). The internal structure of so created four-component system was elucidated by means of an analysis of isotropic area magnitudes in the phase diagram. Conductivity (?), kinematic viscosity (kh) and surface tension (g) studies with the variation in ?w (weight fraction of aqueous phase) show the occurrence of structural changes from water-in-oil (w/o) microemulsion to oil-in-water (o/w). Along with the solubility and partition studies of piroxicam in microemulsion components, the changes in the microstructure of the microemulsion after incorporation of drug have been evaluated using pH, ?, g, kh and density studies. Piroxicam, a poorly water soluble drug, displayed high solubility (1 .0%) in an optimum microemulsion formulation using Ethanol (55.0%), Tween 80 (26.5%), Castor oil (7.5%), and Phosphate buffer (11.0%). The results have shown that the microemulsion remained stable after the incorporation of piroxicam. Fluorescence spectra analysis taking pyrene as fluorescent probe was performed and the results showed that pyrene was completely solubilized in the oil phases of the bicontinuous microemulsions. The fluorescence spectrum of model drug piroxicam was used to probe the intramicellar region of nonionic microemulsion. The results showed that the piroxicam was localized in the interfacial film of microemulsion systems more deeply in the palisade layer with ethanol as the co-surfactant. Keywords: Microemulsion; Piroxicam; Isotropic area; Spectroscopy; Structural changes Introduction Piroxicam is a non-steroid anti-inflammatory compound with analgesic and antipyretic effects, used for the treatment of rheumatoid arthritis, osteoarthritis and traumatic contusions. However, it has been associated with gastrointestinal side effects. It is possible to minimize these problems by developing drug carriers to prevent the direct contact of drug with gastric mucosal or that allow the topical administration of drug (1, 2). Microemulsions are optically isotropic, transparent and thermodynamically stable homogeneous solutions of oil and water, stabilized by addition of a surfactant and usually a cosurfactant (3, 4). These structures have been considerably investigated as drug delivery and carrier system for a wide range of drugs including analgesics and anti-inflammatory and also used to dissolve lipophilic drugs in aqueous medium or hydrophilic drugs in lipophilic medium (4, 5). Oil in water microemulsions have been described as a reservoir system that can inhibit drug release, increasing the topical effect (6). Several mechanisms have been proposed to explain the advantages of microemulsion or the transdermal delivery of drugs (7). First, a large amount of drug can be incorporated in the formulation due to the high solubilizing capacity, with increased thermodynamic activity towards the skin. Second, the permeation rate of a drug from microemulsion may be increased, since the affinity of the drug to th e internal phase in microemulsion can be easily modified, to favor partitioning, using different internal phases and changing the composition of the microemulsion. Third, the surfactant and cosurfactant used in the microemulsion may reduce the various diffusional barrier by acting as penetration enhancers (8, 9). For the selection of components of a biocompatible microemulsion system, the use of non-ionic surfactants has been widely accepted, since these are compatible and retain its utility over a broad range of pH values and may affect the skin barrier function (10-12). Microemulsion comprises different structures (water-in-oil (w/o), oil-in-water (o/w) and bicontinuous) and these help in releasing the drug (13, 14). It is necessary to characterize the microstructure of pure and drug-loaded microemulsion. The changes in the internal structure of a microemulsion can be monitored by analyzing conductivity, viscosity, density, surface tension and the fluorescence probe studies, etc. (15-17). The incorporated drug may or may not influence the microstructure. o/w and w/o microemulsions may show different behavior for the release of both hydrophilic and lipophilic drugs. In the present work, an attempt has been made to construct a microemulsion system, for poorly water soluble non-steroid anti-inflammatory drug piroxicam, comprising castor oil, a non-ionic surfactant Tween 80, a short chain alkanol cosurfactant (ethanol) and phosphate buffer (PB) pH 7.4. The pseudo-ternary phase diagram has been constructed for the chosen system at a constant surfactant:cosurfactant ratio (1:2). The reason for the selection of the particular oil chosen was that the castor oil has a hydroxyl group in addition to unsaturation, making it more polar. Ricinoleic acid is the main component of castor oil and it exerts anti-inflammatory effects (18). Polyoxyethylene fatty acid, stearic acid, oleic acid are used in emulsifiers in oil/water type creams and lotions. Conductivity, viscosity, surface tension and the fluorescence behavior of the pyrene is employed to investigate the gradual changes occurring in the microstructure of microemulsion. Pyrene is popular fluorescent probe which is used to study the microheterogeneous media. The fluorescence spectrum of Pyrene was used to sense the micropolarity of the o/w microemulsion. In this study, it is analyzed that how stability, optical texture and microstructure of microemulsion formulation, is influenced by piroxicam. To improve the solubility of piroxicam, an effort has been made to develop an optimum o/w microemulsion. It is therefore expected that the use of microemulsion formulation may enhance the solubility of piroxicam and prevent its degradation. Materials and Methods Materials Tween 80 (polyoxyethylene sorbitan monooleate), absolute ethanol (99.8 ? %) and castor oil were purchased from Fluka. Pyrene (98 %) was purchased from Sigma-Aldrich. Piroxicam was generously provided by Amson Vaccines Pharma (PVT) Ltd and used without further purification. Phosphate buffer (0.01 M, pH 7.4) was used as the hydrophilic phase. Buffers were prepared using NaH2PO4/Na2HPO4. 0.1M NaOH and HCl were used to maintain the pH of the solution. Methods Microemulsion Preparation The pseudo-ternary phase diagram was mapped (as shown in Fig. 1) using oil (castor oil), surfactant (Tween 80; HLB = 15), cosurfactant (ethanol) and aqueous phase PB (pH 7.4) at 25 ±0.01 ?C with constant surfactant:cosurfactant mass ratio (1:2). The temperature was kept at 25 ±0.01 ?C and was maintained by a Lauda M-20 thermostat. Castor oil was first mixed with Tween 80/ethanol mixture; PB was then added to obtain the desired microemulsion compositions. Transparent, single-phase mixtures were designated as microemulsions. All the samples were stable for over 10 months, remaining clear and transparent. Drug incorporation in Microemulsion Eight microemulsions differing from each other by Fw, were selected from the single-phase region of phase diagram (Fig. 2) with compositions mentioned in table I, to study their potential as drug delivery system. All of them show stability over 10 months and remain clear and transparent. Piroxicam was dissolved into the pre-weight oil component of the system at a concentration of 1% (w/w) under stirring followed by addition of remaining components. Microemulsion Characterization Optical Transparency The homogeneity and optical isotropy of pure and drug loaded microemulsions were examined by a Polarimeter (ATAGO, AP-100 Automatic Polarimeter) and visual examination at room temperature. Centrifugation Thermodynamic stability of pure and drug-loaded microemulsions was tested by carrying out centrifugation at 5500 rpm for 20 min using (Hermle Z200) centrifuge. Surface Tension Surface Tension measurements were made at 25  ±0.010C under atmospheric pressure by Torsion Balance (White Elec. Inst. Co. Ltd.) equipped with a ring having circumference of 4.0 cm. The experimental error was about  ±0.05 mNm-1. Density and Specific Gravity Densities and Specific Gravity of pure and drug loaded microemulsions were measured by making use of an Anton Paar (Model DMA 5000) density meter at 25  ±0.01 ?C. The density meter was calibrated before and after each set of density measurement using the density of air and pure water. Refractive Index The refractive indices of the formulations were determined using a refractometer (ATAGO, RX-5000) by placing 1 drop of solution on the slide. pH The apparent pH of all the selected microemulsions and the drug loaded microemulsion was determined using a pH Meter (WTW 82362 Weilheim) fitted with a pH electrode (WTW A061414035). The temperature was maintained at 25 ±0.01 ?C by a Lauda M-20 thermostat. Conductivity Measurements The effect of the amount of water phase of microemulsion was monitored quantitatively by measuring the electrical conductivity. The electric conductivity (?) was measured by means of a Microprocessor Conductivity Meter (WTW 82362 Weilheim) fitted with an electrode (WTW 06140418) having a cell constant of 1.0 cm-1. The temperature was kept at 25 ±0.01 ?C and was maintained by a Lauda M-20 thermostat. Conductivity measurements were carried out by titration of oil and surfactant/cosurfactant mixture with buffer (along the dilution line AB in Fig. 1). Further the conductivity of selected and drug loaded microemulsions was also measured. The error limit of conductance measurements was  ±0.02 ?scm-1. Viscosity Measurements Viscosities were measured with calibrated Ubbelhode viscometer at 25 ±0.1 ?C. For each measurement, the viscometer was washed, rinsed and vacuum dried. To follow the viscous behavior of the microemulsions, flow time was measured for all the selected and drug-loaded microemulsions (1 wt% drug). The error limit of viscosities measurements was  ±3%. Absorption and Steady-State Emission Measurements The absorption and steady-state fluorescence spectra were recorded using a Perkin Elmer Lambda 20 spectrophotometer and a Perkin Elmer LS 55 luminescence spectrometer, respectively, both with an external temperature controlled cell holder at a temperature of 25.0 ±0.1 °C. The fluorescence emission spectrum of pyrene (excitation at 340 nm) was used to obtain the ratio of intensities of the first to the third vibronic peaks (I1/I3). Good resolution of the bands was obtained at the slit width (ex. 5.0nm, em. 5.0 nm). The scan range used was from 350-500 nm. The Photo Multiplier tube voltage was kept at 665V. The concentration of pyrene was 1.0 ?M. The intensities for I1 and I3 are taken at 373 and 384 nm, respectively. The fluorescence emission spectrum of piroxicam at ?exc 370 nm was obtained where the emission and excitation slits were fixed at. 7.0 nm. The scan range used was from 390-650 nm. The concentration of piroxicam was 10.0 ?M. To quantify the solubilization of piroxicam in micellar media of Tween 80-Ethanol system, differential absorbance measurements were made in such a way that drug (piroxicam) solution of a particular concentration (1.0-10-5M) was kept on reference side and the Tween 80-Ethanol-Piroxicam solution on the sample side in the spectrophotometer. Partition Coefficients Oil/buffer partition coefficient was determined by dissolving 20 mg piroxicam in 2ml Castor Oil. Buffer was added in 1:1 ratio (v/v). The mixture was shaken for 10 min and centrifuged for 2 hours. The two layers were separated and the content of piroxicam in aqueous layer (PB) was assayed by UV-Visible spectrophotometer at 371 nm. The final content of drug in the lipophilic phase was calculated by subtracting the content of piroxicam in aqueous phase from initial loaded content of drug in the lipophilic phase. Further, the effect of presence of Tween 80 and ethanol on the partition of piroxicam in oil/buffer was studied by adding 5% (w/v) of each Tween 80 and ethanol. Results and Discussion In the present system, microemulsion was prepared using Castor oil (fatty acid), which induces highly permeable pathways in the stratum corneum (18-20). Tween-80 is a widely accepted non-ionic surfactant, used in many pharmaceutical formulations (21-23). The cosurfactant (ethanol) is used to study the one phase microemulsion region. The presence of alcohol overcomes the need for any additional input of energy. These properties make the components useful as vehicles for drug delivery (24-26). In the absence of aqueous phase, a solution-like oily phase consisting only of surfactant, oil, and ethanol exists. Ethanol interacts with the ethoxylated head groups of the Tween 80 by hydrogen bonding and affects its critical packing parameter (CPP). When water is progressively added to the concentrate it facilitates the organization of the hydrated head groups of the surfactant into a polar core while the fatty acid tails are immersed in the oil continuous phase. The ethanol suppresses formation of lyotropic liquid crystals. Any free aqueous phase is entrapped in the microstructures. Thus, w/o microstructures are formed. Upon further dilution, the reversed nanostructures grow and convert into a bicontinuous phase and finally invert into o/w microstructures without phase separation. Phase Studies Fig. 1 shows the pseudo-ternary phase diagram and area of existence of microemulsion for Tween-80/ethanol/castor oil/phosphate buffer. Microemulsion in the present study formed spontaneously at ambient temperature when their components were brought in contact. Phase behavior investigations of this system demonstrated the suitable approach of determining the water phase, oil phase, surfactant concentration, and cosurfactant concentration with which the transparent, 1-phase low-viscous microemulsion system was formed. The phase behavior, as shown by figure 1, manifests a two-phase region, a three-phase region and a large single-phase region which gradually and continuously transformed from buffer rich side of binary solution (buffer/surfactant micellar phase) of pseudo-ternary phase diagram towards the oil rich region. This stresses a continuous transition from a water rich compositions to oil swollen micelles. The phase study revealed that the maximum proportion of oil was incorporated in microemulsion systems when the surfactant-to-cosurfactant ratio was 1:2. From a formulation viewpoint, the increased oil content in microemulsions may provide a greater opportunity for the solubilization of piroxicam. Eight microemulsions (1-8) were selected from the single-phase isotropic region (Fig. 2), with compositions mentioned in table I. Selected Microemulsion (ME) was further analyzed by conductivity, viscosity, density, surface tension, refractive index and pH. The values of measured parameters have been presented in table II. Conductivity Measurements Conductometry is a useful tool to assess microemulsion structure. Conductivity studies have explained the existence of a characteristic zone with an isotropic microemulsion domain in a continuum. Determination of electric conductivity (s) as a function of weight fraction of aqueous component Fw (% wt) for the oil, surfactant/cosurfactant mixture along the dilution line AB (shown in Fig. 2) has been carried out. The results of variation of s vs Fw (% wt) are shown in Fig. 3 (a). The behavior exhibits profile characteristic of percolative conductivity (27-29). The conductivity is initially low in an oil-surfactant mixture but increases with increase in aqueous phase. As the volume fraction of water increases, the electrical conductivity of the system slightly increases as well, until the critical Fw is reached. At this stage, a sudden increase in conductivity is observed. This phenomenon is known as percolation, and the critical Fw at which it occurs is known as percolation threshold Fp (27). The value of conductivity below Fp suggests that the reverse droplets are discrete (forming w/o microemulsion) and have little interaction. Above Fp the value of s increases linearly and steeply till it touches the value of Kb. The interaction between the aqueous domains becomes progressively more important and forms a network of conductive channel (bicontinuous microemulsion) (30). Rapid increase in conductivity beyond the percolation threshold (Fp ? 6%) up to approximate value of 20% of Fw indicates the existence of network of conductive channels, which corresponds to the formation of water cylinders or channels in an oil phase due to the attractive interactions between the spherical micro-droplets of water phase in the w/o microemulsion. Increasing water content above Fb (Fw > 20%), the s shows a dip in the measured values which may be due to strong attractive forces as system becomes more viscous (16, 30).Fig. 3 (b) depicts the variation of log s vs weight fraction of water (Fw). The change in the slope of log s can be attributed to the structural transition to bicontinuous from w/o (23), nearly at Fw = 6%. The transition takes place once the aqueous phase becomes continuous phase i.e. at Fb. This is in line with the observation made in phase study. Figure 3(a) illustrates occurrence of three different structures (namely w/o, bicontinuous, o/w). The conductivity of the microemulsions containing more than 20 wt% water decreased significantly, probably due to the higher viscosity. The percolation threshold can be determined from the plot (ds/dFw), as a function of the water weight fraction, Fw (% wt) (30). A maximum in the first derivative of conductance Fw at ~12wt % water is observed (Fig. 4) confirming the presence of percolation behavior (bicontinuous microstructure) in this region (31). The electric conductivity of pure selected and drug loaded microemulsion (1.0%) is given in table II. A comparison of two systems shows that drug incorporation does not affect the microstructure of the microemulsion. Viscosity Measurements To avoid the ambiguity of non-Newtonian flow behavior of microemulsion the flow time has been used as an index of viscosity (32). Flow time of oil, surfactant/cosurfactant mixture along the dilution line AB (shown in Fig. 2), was measured as a function of weight fraction of water Fw (wt %) and is shown in Fig. 5. Similar trend has been observed for the viscosity of oil, surfactant/cosurfactant mixture as a function of Fw (Fig. 6). The rapid change in the viscosity is probably due to the change in the microstructure of the microemulsion. The change in the internal structure could be due to either the change in the shape of droplets or may be due to the transition from w/o to bicontinuous microemulsion. It is well known that increase of volume fraction of dispersed phase in microemulsion increases viscosity of the system (33). For the system studied viscosity increases with increase in Fw (wt% of aqueous phase). Difference in the viscosities is more profound for lower water content values in comparison to the dilute system. The microemulsion system is turning to be more viscous with addition of water and thus may help in the slow diffusing of drug at infinite dilution. The microemulsion system thus, shows a structural change from oil continuous system to water continuous, which has higher viscosities than the former (34). The plots of hk (kinematic viscosity), d2?/d2Fw and 1/? d?/dFw versus Fw reflect that the transition occurs at ~11% weight fraction of aqueous phase (Fig. 6). The transition point of surface tension, conductivity and viscosity plots coincides well at ~11% weight fraction of aqueous phase and confirms the presence of percolative behavior. Surface Tension The surface tension increases linearly over the same range of water content (Fig. 7), but two breaks (at ~7.0 and ~20 wt% water) suggest that structure changes occur at these compositions. The surface tension measurements showed increment, when measured as a function of weight fraction of aqueous component, except for the ~12% weight fraction where the value suddenly decreased and thereafter a regular increase was observed. This low surface tension value showed the presence of bicontinuous microemulsion between oil and water rich system, which is because of presence of self-assembled organize microstructure in it (14, 35). The results coincide well with the electric conductivity and viscosity measurements. It can be assumed that the added alcohol (ethanol) is incorporated in the interfacial structure in such a way that more water is on the outside of the oil drops, causing the increase in surface tension. Incorporation of drug showed a negligible change in the surface tension measure ments, therefore indicting the possibility of piroxicam molecules into the palisade layer on the inner side of microemulsion. Fluorescence Measurements In the case of oil-in-water microemulsions, the steady-state fluorescence technique was successfully applied (36). Fluorescence measurements of the hydrophobic probe mainly depend on the polarity of the medium and hence in bicontinuous microemulsions it is a good indication of the polarity of the microenvironment in the microemulsion structure (37). The fluorescence spectra for pyrene molecule in water, individual oil phase, in alcohols, in ethanol/oil and in all the selected microemulsions are shown in Figure 8. There are four principal vibronic bands in the fluorescence spectrum (Fig. 8a), labeled I to IV. The peak intensity ratio I1/I3 in the steady-state fluorescence spectra is a measurement of the relative polarity of pyrenes environment (17). Since pyrene reactant is substantially more soluble in oil phases, I1/I3 is expected to be lower in these phases (38). In the present work, for oil phase, the I1/I3 value is 0.68. In relatively polar methanol and ethanol media, I1/I3 values were found to be 1.20 and 1.09 respectively. Water is a highly polar solvent; the solubility of pyrene in this solvent is less than 2 ?M. Hence the possibility of formation of excimer leading to I3 signal is extremely low in water. Experimentally I1/I3 value is 1.70 was obtained for this medium. Plot of I1/I3 versus weight fraction of aqueous component composition in microemulsion is shown in Figure 9. The value of I1/I3 varies between 0.85 and 0.91, which is comparable to a change from oil to water (0.68 and 1.70, respectively). The I1/I3 fluorescence ratios of pyrene strongly suggest that this probe resides in microenvironments of polarity much lower (oil phase) than that of water or alcohol (39). The polarities of these microphases are similar to those of cosurfactant/oil mixtures (0.94). The following generalizations may be made regarding the fluorescence probe behavior in bicontinuous microemulsions. The I1/I3 values obtained by fluorescence measurements for all the stable bicontinuous microemulsions are closer to 0.88. These results suggest that pyrene is efficiently segregated from the water phase (40). The I1/I3 values in bicontinuous microemulsions systems are closer to the respective pure oil phase. This is due to complete solubility of pyrene in oil phases of the bicontinuous microemulsions. We conclude that all the microemulsions have separate oil microphases, in which pyrene resides. Fluorescence Behavior of Piroxicam The fluorescence spectra for piroxicam molecule in water, individual oil phases, in surfactant/cosurfactant mixture (1:2) and in the optimum microemulsion system are shown in Figure 10. For oil phase the emission maxima (lem) is 465nm. In S/CoS (1:2) system lem is 451nm. Water is a highly polar solvent; the solubility of piroxicam in this solvent is low than 10 ?M. The lem of piroxicam in water is 442nm. The emission maximum in bicontinuous microemulsion system is (462nm) closer to the respective pure oil phase. The results showed that the piroxicam was localized in the interfacial film of microemulsion systems more deeply in the palisade layer. Partition Coefficient Partition coefficients influence drug transport characteristics which involve drug absorption, retention, distribution and elimination. Since drugs are distributed by the blood, they must penetrate and traverse many cells to reach the site of action. Hence, partition coefficients will determine what tissues a given compound can reach. Oil/buffer Partition Coefficients The partition coefficient (log p) of piroxicam in oil/buffer is 5.03 ±0.20. The presence of ethanol (5% in buffer) does not affect the partition coefficient (data shown in table III) whereas Tween 80 (5% in buffer) reduces the log p. The presence of surfactant reduces the concentration of drug in oil. Thus, solubility and partition studies indicate that piroxicam may be present at interface. The drug is entering into the palisade layer on the inner side of droplet which may help to increase the solubility of piroxicam. The partition coefficients were calculated using equation 1 (41); where A(org) is the absorbance of the organic layer, A(aq) is the absorbance of the aqueous layer, Vf(org) is the final volume of the sample from the organic layer, V(org) is the volume of the aliquot from the organic layer, Vf(aq) is the final volume of the sample from the aqueous layer, V(aq) is the volume of the aliquot of the aqueous layer. Micelle/buffer Partition Coefficient Figure 11 shows the differential absorption spectra of drug (piroxicam) in presence of various concentrations of Tween 80 having constant S/CoS ratio (1:2). The buffer-micelle partition coefficient Kc (dm3 mol-1), a useful parameter to quantify the solubilization of piroxicam in micellar media of Tween 80-Ethanol system, can be calculated by using equation 2 (42). Here Ca is the drug concentration (1.0-10-5M), Csmo represents Cs-CMC0 (CMC0 is the CMC of Tween 80 in water i.e. 11.0mM), ?A? is the differential absorbance at the infinity of Cs. Kc can be obtained through intercept and slope values of the straight line plot of 1/?A against 1/ (Ca+ Csmo), as shown in Figure 12. The value of Kc is given in table IV. The dimensionless partition coefficient p is related to Kc as p = Kc.nw, where nw is the number of moles of water per dm3 (55.5 mol dm-3), and is reported in table IV. The standard free energy change of the transfer of additive, from bulk water to micelle can be calculated using the following relation (equation 3): Here T is absolute temperature and R is the gas constant. The value of ?G °p for the piroxicam, using p is reported in table IV. High negative value of indicates the ease of penetration of drug inside the micelles. This is clearly exhibited by the higher values of p and more negative for piroxicam, as shown in table IV. Tween 80 is nonionic surfactant and there is no electrostatic interaction, the hydrogen bonding between the polyoxyethylene groups of Tween 80 and piroxicam makes the complex (Tween 80-piroxicam) more hydrophobic, which corresponds to high ?G °p value. Conclusion The pseudo-ternary phase diagram and area of existence of microemulsion for Tween 80/ethanol/castor oil/buffer was delineated. The conductivity and viscosity studies along the dilution line (in phase diagram) depict the structural transition from w/o to o/w via bicontinuous phase at ~11% ?w (wt% fraction of aqueous phase). Among the eight selected microemulsions, ME was found to be optimum for the incorporation of piroxicam. After the incorporation of the drug, microemulsion remained stable and optically clears with no phase separation. The surface tension and fluorescence studies indicated that the drug may reside at the interface of oil and aqueous phase. The drug is entering into the palisade layer on the inner side of the droplet, resulting in controlled release of drug. Thus, we can conclude that this microemulsion system helps in increasing the solubility of a highly hydrophobic drug, with the help of hydrophobic component of microemulsion and lipophilic part of surfactant. In addition, the formulation can be explored with high concentration of drug. Pharmaceutically usable microemulsion system was prepared from water and castor oil with a constant amount of Tween-80 and ethanol at a mass ratio of 1:2. Its type and structure was examined by measuring surface tension, viscosity, electric conductivity, and the fluorescence techniques were assessed. Results of conductivity, viscosity, density and surface tension measurements confirm the prediction of a percolation transition to a bicontinuous structure. In future, the ability to determine type and structure of such microemulsion system could enable partitioning and release rates of drugs from microemulsion to be predicted. Acknowledgement The financial support of Quaid-i-Azam University and Higher Education Commission of Pakistan is duly acknowledged. References Lopes LB, Scarpa MV, Pereira NL, De Oliveira LC, Oliveira AG. Interaction of sodium diclofenac with freeze-dried soya phosphatidylcholine and unilamellar liposomes. Revista Brasileira de Ciencias Farmaceuticas/Brazilian Journal of Pharmaceutical Sciences. 2006;42(4):497-504. Park ES, Cui Y, Yun BJ, Ko IJ, Chi SC. Transdermal delivery of piroxicam using microemulsions. Arch Pharmacal Res. 2005;28(2):243-8. Yuan Y, Li Sm, Mo Fk, Zhong Df. Investigation of microemulsion system for transdermal delivery of meloxicam. Int J Pharm. 2006;321(1-2):117-23. Sarciaux JM, Acar L, Sado PA. Using microemulsion formulations for oral drug delivery of therapeutic peptides. Int J Pharm. 1995;120(2):127-36. Ristsehel WA. Experimental and Clinical Pharmacol. 1991. Mehta SK, Kaur G, Bhasin KK. Analysis of Tween based microemulsion in the presence of TB drug rifampicin. Colloids and Surfaces B: Biointerfaces. 2007;60(1):95-104. Sebastien H, Devin VM, Mark GA, Mark RP. Microfabricated microneedles: A novel approach to transdermal drug delivery. J Pharm Sci. 1998;87(8):922-5. Sintov AC, Botner S. Transdermal drug delivery using microemulsion and aqueous systems: Influence of skin storage conditions on the in vitro permeability of diclofenac from aqueous vehicle systems. Int J Pharm. 2006;311(1-2):55-62. Spernath A, Aserin A. Microemulsions as carriers for drugs and nutraceuticals. Adv Colloid Interface Sci. 2006;128-130:47-64. Lawrence MJ, Rees GD. Microemulsion-based media as novel drug delivery systems. Adv Drug Delivery Rev. 2000;45(1):89-121. Là ³pez A, Llinares F, Cortell C, Herrà ¡ez M. Comparative enhancer effects of Span ®20 with Tween ®20 and Azone ® on the in vitro percutaneous penetration of compounds with different lipophilicities. Int J Pharm. 2000;202(1-2):133-40. Fang JY, Yu SY, Wu PC, Huang YB, Tsai YH. In vitro skin permeation of estradiol from various proniosome formulations. Int J Pharm. 2001;215(1-2):91-9. Krauel K, Davies NM, Hook S, Rades T. Using different structure types of microemulsions for the preparation of poly(alkylcyanoacrylate) nanoparticles by interfacial polymerization. J Controlled Release. 2005;106(1-2):76-87. Mehta SK, Kaur G, Bhasin KK. Incorporation of antitubercular drug isoniazid in pharmaceutically accepted microemulsion: Effect on microstructure and physical parameters. Pharm Res. 2008;25(1):227-36. He D, Yang C, Ma M, Zhuang L, Chen X, Chen S. Studies of the chemical properties of tri-n-octylamine-secondary octanol-kerosene-HCl-H2O microemulsions and its extraction characteristics for cadmium(II). Colloids Surf A. 2004;232(1):39-47. Podlogar F, GasÃÅ'Å’perlin M, TomsÃÅ'Å’icÃÅ'Å’ M, Jamnik A, RogacÃÅ'Å’ MB. Structural characterisation of water-Tween 40 ®

Friday, October 25, 2019

Graduation Speech -- Graduation Speech, Commencement Address

Class of 2012, tonight is the last time we will share together for many years. After tonight, we will begin a new chapter in our lives. This chapter will lead us away from each other, but the memories we've shared will continue to stay. The years behind us have been full of challenges and rewards; these experiences will be there to guide us as we branch out into the world. Let's take a moment to think back to the people and times that shaped us the last four years. Every teacher deserves a "thank you" for helping us to reach our goal of graduation. The love and support of our families has been greatly appreciated. But truly, the main ingredient of our high school experience has been our peers. We all faced hardships, but we were able to overcome them, together. And now, here we are once again, together. Homecoming, tolo, football games, pep assemblies and spirit weeks ignited us as young freshman. When we became sophomores, the blaring of the fire alarm became our wake-up call. Only after wiping the drool off our desks and hurrying out to the field did we realize that this wa...

Thursday, October 24, 2019

Intercultural Communication and Conflicts Essay

The communication between different cultures is very difficult. Intercultural communication can lead to misunderstanding and confusion. You may offend someone without even knowing it. Nonverbal communication is challenge as well such as handshakes, eye contact, hug, and etc. These problems happened so many times from my fiancee who is from America and me who is from South Korea. One day, my father visited to our place for holiday. When my father walked into our place, my fiancee was lying on the sofa and then he said â€Å"Hi. In Korean culture, when adults come to you, you need to stand up and bow to them. That moment, my fiancee’s behavior was disrespectful to my father. This tells us that we grew up differently since we have different culture background. However, we both have the attitude where we like to learn about each other cultures. It gives us a better understanding and respect more. To me, language barrier is one of issue with communication. When I moved to America, I barely spoke English and I was really afraid of speaking with other people, especially in English; however, time went by, as went to high school, college and join in the Army in America, I became more interactive in communication with people. Also, my fiancee helps me to learn and correct my English skill. Interpersonal communication Thousands of people use more online email, texting, Facebook, twitter, and etc. to communicate now, because it’s easier and faster to communicate to others. On the other hand, online communications can be bad. More likely, face to face communication can be avoided. I realized that most people use smart phone anytime and anywhere now. Sadly, it happens during class, meeting, dating, waiting, and dining. In fact, one of my nieces who is 6 years old refused to talk and listen to me when I discipline her. Instead face to face communication, she wanted to text me to say â€Å"sorry. † I didn’t accept her apologize because I believe in true meaningful interpersonal communication should be face to face communication.

Wednesday, October 23, 2019

Cartoon Endorsement

Prepared by: Fariha Tazin, Lecturer, Faculty of Business Studies (Marketing) Proposed Title: CARTOON ENDORSEMENT: Efficacy on Kids Market Abstract: Kids are bombarded with various forms of promotional activities by marketers of food products. Today’s kids are very much aware of the fashion trend and who’s ever has taken them to market has been observed the marketing power of the popular cartoon characters. The purpose of this research study will be to find out whether cartoon strengthens children to buy more or not. Qualitative research approach will be used to carry out this research study.This study will set out to find the amount of influence that cartoon endorsers have on children. As there have been few academic literatures on the topic of the effectiveness and usefulness of cartoon endorsement in the field of advertising, It has been set as the main goal of this research studies to explore the weight of cartoon endorsement as a promotional technique in Bangladeshi markets. 1. Introduction: A child wakes up in his Disney character pajamas, rolls out of his Barney sheets, his toothbrush, toothpaste and perhaps even his soap covered in cute licensed characters.Gathering up his Pokemon cards and strapping on his Doraemon backpack, he heads off to school. But the Commercialism does not stop even in the schoolyard. Leveraging the endorsement of products by popular cartoons, as a marketing practice, is a common phenomenon. Cartoon endorsement concept has been derived from the idea of celebrity endorsement. The retailing segment is displaying immense business potential for these younger segments. Retailing for kids, be it branded or unbranded, has emerged as a tremendous market in Bangladesh.The kids retail market is immense, with a huge variety available in the clothing, accessories and footwear sections. Some of the products that are available in the kid’s accessories segment include fashion accessories, watches and even kids’ design er jewellery, not to mention toys, books, games, electronics, education aids. Dora the Explorer, Mickey Mouse and all the other staples of morning TV are part of the world’s greatest sales team — because when they’re on the package, kids start yelling for it. 2. Aim: to examine the effect of Cartoon endorsement on kids market. . Objective: a. To find out that whether there is a relationship between cartoon endorsement and the buying behavior of children. b. To analyze the benefits of having cartoon endorsement on products. 4. Research Questions: a. How retailers use cartoons on their variety of products? b. How kids respond to these endorsed products? c. How unbranded products are having benefited from this Cartoon endorsement of children market? d. Is there any negative outcome of this marketing that can badly affect children? 5. Literature Review:Advertisers often choose celebrities who are physically attractive allowing them to get benefit both from the statu s and physical appeal of different celebrities (Singer 1983). Most of the advertisements which get on air contain characters that are attractive. It has been observed that consumers often form positive opinions about such characters. Apart from this, it is seen that attractive communicators are doing well in changing the beliefs of the consumers (Baker and Churchill 1977; Chaiken 1979; Debevec and Kernan 1984) and increasing the purchase intents (Friedman et aI. 976; Petroshius and Crocker 1989; Petty and Cacioppo 1980) as compared to those characters that are unattractive. In one of the study by Story and French revealed that 75% of the purchase requests take place in a supermarket environment. 6. Methodology: The data will be collected using the questionnaires. For this purpose different school, neighborhoods and shopping malls will be visited to collect the data. This research will be conducted by taking the perspective of the parent’s that how they their children behaves when they encounter the cartoon endorsed product.The sample size for carrying out this research consisted of 50 respondents. 6. 1 Data Collection a) Primary Data Collection In this research study the primary data will be collected through survey questionnaires. For this purpose questionnaires will be distributed to those parents whose children lies between the ages of 3 to 8 years. So it is possible to define that age group of children who are dependent on their parents for buying decisions. b) Secondary Data Collection Secondary data will help us in determining the various dimensions of the variables under study.The secondary data for this research study will be collected from different journals, books, researches and websites. Mostly the data will be collected from previously published journals and researches. 7. Conclusion Young children, in particular, have difficulty in distinguishing between advertising and reality in ads, and ads can distort their view of the world. Additiona lly children are unable to evaluate advertising claims. Children represent an important demographic to marketers because they have their own purchasing power, they influence their parents' buying decisions and they're the adult consumers of the future.Marketer tries to draw children’s attention through various means like TV, Magazines, Stickers, etc. Obviously attracted children by the marketing practices; get adversely affected most of the time. I expect this research to contribute to debates of the idea will be to find out the relationship between the cartoon endorsement and children impulse buying behavior, more specifically that whether those products are bought more impulsively by the children which have their favorite cartoon characters on them.References: Edward Martin, â€Å"Cartoon characters influence kids† [online], Health Revelations, 2009-2010 [cited July. 16, 2010], available from World Wide Web: http://healthrevelations. com/2010/07/16/cartoons-endorse-f ood/ a. AsimTanvir, † IMPACT OF CARTOON ENDORSEMENT ON CHILDREN IMPULSE BUYING OF FOOD: A PARENT’S PERSPECTIVE† The Institute [online], VOL 4, [cited JUNE, 2012], available from World Wide Web: http://www. ijcrb. webs. com. html b. Bellenger, D. N. , Robertson, D. H. & Hirschman, E. C. 1978. Impulse buying varies by product. Journal of Advertising Research. Vol. 18. No. 6, 15-18 c. Gardner, M. P. & Rook, D. W. 1988. Effects of impulse purchases on consumers’ affective states. Advances in Consumer Research. Vol. 15, 127-130 d. Bardia Yousef hakimi & Abed Abedniya & Majid Nokhbeh Zaeim . , â€Å"Investigate the Impact of Celebrity Endorsement on Brand Image† European Journal of Scientific Research, ISSN 1450-216X Vol. 58 No. 1 (2011), pp. 116-132,  © EuroJournals Publishing, Inc. 2011, available from the : http://www. eurojournals. com/ejsr. htm e. Aaker, D. A and Myers, J. G (1987), Advertising Management, 3rd edition, Englewood Cliffs, New Jersey: Prentice-Hall, Inc

Monday, October 21, 2019

Free Essays on Operation Vittles

In June 1948 Soviets authorities halted all entrances or exits to the western-controlled section of Berlin by land and by water. A 20 mile-wide air corridor across the Russian zone of Germany was the only remaining access route into the city. For the next eleven months the Western Allies supplied West Berliners with the necessities of life. The unofficial name given to the operation was Operation Vittles and it began on June 26. 4,500 tons of food, coal, and other material needed for daily maintainence of a minimum level of existence was fulfilled with only 80 tons carried by USAF C-47s on June 26. However, this force was quickly increased by the aid of U.S. Navy and Royal Air Force cargo aircraft. On October 15, 1948 a unified command known as the Combined Airlift Task Force under Maj. Gen. William H. Tunner, USAF was created to promote increased safety and cooperation between the separate U.S. and British airlift efforts. Three SAC bomb groups were sent to Europe placing Soviet targets within B-29 range. Three airfields were used within Berlin consisting of Tempelhof in the U.S. sector, Gatow in the British sector, and Tegel within the French sector. As of September 1948, the unloading of C-47s at Tempelhof was the most predominating form of the airlift until it was replaced by the C-54s which was capable of hauling ten tons. A cross-sectional view of flight into Berlin was arranged simultaneously which allowed the landing at the rate of one plane every 3 minutes; this was later improved to two levels which still maintained the same landing rate. Airlift pilots flew under an extremely rigid system of traffic control which required each pilot to fly an exact route at predetermined speed as well as altitude in order to make a successful landing or otherwise return to its base in West Germany. At midnight on May 12, 1949, the Soviets reopened the land and water routes into Berlin. However, the airlift progressed until September 3... Free Essays on Operation Vittles Free Essays on Operation Vittles In June 1948 Soviets authorities halted all entrances or exits to the western-controlled section of Berlin by land and by water. A 20 mile-wide air corridor across the Russian zone of Germany was the only remaining access route into the city. For the next eleven months the Western Allies supplied West Berliners with the necessities of life. The unofficial name given to the operation was Operation Vittles and it began on June 26. 4,500 tons of food, coal, and other material needed for daily maintainence of a minimum level of existence was fulfilled with only 80 tons carried by USAF C-47s on June 26. However, this force was quickly increased by the aid of U.S. Navy and Royal Air Force cargo aircraft. On October 15, 1948 a unified command known as the Combined Airlift Task Force under Maj. Gen. William H. Tunner, USAF was created to promote increased safety and cooperation between the separate U.S. and British airlift efforts. Three SAC bomb groups were sent to Europe placing Soviet targets within B-29 range. Three airfields were used within Berlin consisting of Tempelhof in the U.S. sector, Gatow in the British sector, and Tegel within the French sector. As of September 1948, the unloading of C-47s at Tempelhof was the most predominating form of the airlift until it was replaced by the C-54s which was capable of hauling ten tons. A cross-sectional view of flight into Berlin was arranged simultaneously which allowed the landing at the rate of one plane every 3 minutes; this was later improved to two levels which still maintained the same landing rate. Airlift pilots flew under an extremely rigid system of traffic control which required each pilot to fly an exact route at predetermined speed as well as altitude in order to make a successful landing or otherwise return to its base in West Germany. At midnight on May 12, 1949, the Soviets reopened the land and water routes into Berlin. However, the airlift progressed until September 3...

Saturday, October 19, 2019

Automatic Flight Control Systems Engineering Essay

Automatic Flight Control Systems Engineering Essay We live in a world where technology is, if not being improved, developed by the second. Everyday new improvements, inventions and discoveries are made. One industry that is always on the lead when it comes to new inventions and innovations is the Aviation Industry. Over the years, aircrafts have been facing major improvements on the structure, fuel efficiency, life-span, range of flight. But one of the best improvements that have been done on every aircraft (commercial) that had the biggest impact in the Aviation Industry and most probably the main reason why the industry has been booming up is the improvements done in the Avionics section, specifically the Automatic Flight Controls. In the beginning, Pilots were trained to fly the aircrafts alone. But after several years, it is now the pilots programming the computer, telling it where to fly, at what altitude, etc. This computer is the AFCS (Automatic Flight Control System). In today’s modern world of flying, it is the AFCS who is technically flying the aircraft, from cruising to landing, and for some until parking. The AFCS has a lot of advantages when compared to human pilots when it comes to flying. Here are some of them: The AFCS has the ability to overcome deficiencies when it comes to stability and control. The AFCS improved the handling qualities. Such as, when the airspeed or the altitude of the aircraft needs to be constant. The AFCS is more accurate and hence is able to carry out several tasks that the pilot is not able to do. * Source: Emirates Aviation College’s Automatic Flight Control Systems Book (Chapter 3.1.3) To get a better understanding of the AFCS, the different parts of it will be discussed, such as the Autopilot System, Flight Director System, Auto Throttle System and etc. The information about the AFCS will be based on one of Boeing’s classic aircrafts, the 737-500. FLIGHT MANAGEMENT SYSTEM (FMS) The Flight Management System is navigation, combined flight control, a Built-In Test Equipment (BITE) and a guidance system. The FMS provides control and operation of five independent subsystems to provide lateral navigation (LNAV) and vertical navigation (VNAV) for performance management and optimum flight profiles. The Flight Management System is not labeled to any control panel or any single component as it is an integration of five independent subsystems. These subsystems are: Digital Flight Control System (DFCS) Inertial Reference System (IRS) Autothrottle Electronic Flight Instrument System (EFIS) Flight Management Computer System (FMCS) * Source: United Airlines’ Boeing 737-322/522 (page 6, Chapter 22-2, Oct ’99) from Emirates Aviation College Library This system was designed to increase fuel efficiency, safety and decrease workload. For both pilots, this means that they can select full FMS operation or Autopilot Flight Director System (AFDS) for a complete automatic flight. They can even use the Control Display Units (CDU) to pr ovide, for manual flight, reference information. Management and operation is totally under the control of the flight crew. There are only certain operations that can only be implemented by the flight crew. They are: landing rollout steering, thrust reversal, speed brake operation, altitude selection, landing gear and flap operation, instrument landing system (ILS) tuning, thrust initiation, brake release, airplane rotation and steering during takeoff roll.

Friday, October 18, 2019

Write a research paper regarding the FDA health regulation about

Write a regarding the FDA health regulation about Sanitary Transportation of Human and Animal Food - Research Paper Example In 1994, an outbreak of disease was seen across states because of contamination during transportation of ice-cream. Before this in 1974, corn fodder meant for animals was contaminated with lead monoxide during transportation as well . Such instances shows that improper transportation has detrimental health impacts on the consumers (Prishable logistics,2011). In 1999, the congress enacted the SFTA. SFTA directed the department of Transportation to prescribe regulations against and protection of these food and food additives from harmful transportation of food and food additives. Followed by this the FDA also released the FSMA act according to which food facilities should have a plan to prevent food contamination, protect food from bioterrorism, recognize potential hazards and take steps to address the same and lastly monitor the entire procedure of food production and transportation and to correct anomalies if present as well. In 2013, the FDA also put its focus on transportation of food meant for animals including pet food and food meant for livestock or food-producing animals since following the 1974 occurrence when contaminated fodder led to disease outbreak among animals. The procedure followed by the facilities that manufacture such handle, handle and transport them is the same as those facilities producing food for human consumption. The most important thing that the FDA primarily concentrated is on not only the safe and hygienic transportation of food but also on its purity. Purity of food means that it is free from any kind of contamination and adulteration since both of these are harmful in nature. Often during food transportation inadequate facilities are provided and such ill-handled food is often found to be adulterated and through the regulation the FDA aims at mitigating food safety risks. Safe transportation of human and animal food is of major concern for the FDA. The FDA reports

Summarize the importance of a business impact analysis across the Assignment

Summarize the importance of a business impact analysis across the supply chain (value chain) - Assignment Example , production is efficient and time is saving making it beneficial to outsource products from china other than production because the time saved on production is used for making sales, marketing and developing the business. It is important to note that Chinese cost of raw materials and labor is low. On the other hand, the option of shipping raw materials by air might be very expensive while shipping by sea is slower. For instance, the shipment could be too heavy to be shipped by air making it fair for production to be outsourced from China. The benefit achieved in importing products from China is that the inspection is carried out by a third party so as to enable the mistakes in the products to be ironed out before reaching the US markets. Another benefit is that, quality control in the production plant is put in place. The Chinese companies also conduct education for importers (Power et al., 2006). On the contrary, the importers can import a dangerous product which will consequently lower the volume of sales. In this regard, faults in the product can harm the standing of the firm owing to meager quality product. Risks of terrorism and currency fluctuations should be put into consideration. Other risks include; the uncertainty of quality of products and challenges of keeping the Chinese chain

Theory of Human Caring Essay Example | Topics and Well Written Essays - 1750 words

Theory of Human Caring - Essay Example According to Watson (2009), "nursing is a lifetime journey of caring and healing, seeking to understand and preserve the wholeness of human existence, and to offer compassionate, informed, knowledgeable human caring to society and humankind." Thus, nurses play an important role in the healing of human suffering. In this essay, role of Watson's theory in caring of patients in nursing profession will be discussed through review of a particular case and reflection. Case scenario 55 year James was transferred to the neurology ward from neurosurgical ICU to which he was admitted one week ago with right sided hemiplegia following stroke. Besides right sided hemiplegia, the patient had bladder and bowel incontinence, pneumonia and depression. I was one of the nurses assigned to take care of the patient. The patient stayed in the stroke rehabilitation ward for 4 weeks. During the first week in the ward, I found James to be depressed and frustrated. His only family member with him was his wif e. I found out from the couple that they had 2 sons, who were married and stayed in different countries. They had not come down because the parents did not want to trouble them and hence did not deliver proper information. During my sessions of nursing care I convinced the patient that their sons be asked to come down as it would make the patient feel a lot better. I finally managed to convince them to do so in the second week and when their sons came down, the patient was a lot better psychologically. The patient was a spiritual person and believed in Christianity. He missed attending church regularly. I allowed him to offer prayers by arranging a father to meet him every week. This uplifted the psychological and spiritual morale of the patient. As he improved, I asked his wife and sons to contact a few friends of James and asked them to meet him in the rehabilitation center. James was very much upset about his physical deficiencies because of stroke, especially the bowel and bladd er incontinence. I instilled lot of confidence and hope in the patient and told him that recovery occurs with good positive outlook and physiotherapy. The patient got discharged after 4 weeks. When he came for review after 4 weeks of discharge, he was a lot more improved physically and psychologically and confident person. Jean Watson and her theory Jean Watson, an eminent nurse educator and theorist has contributed significantly to the profession of nursing through her famous theory, the Theory of Transpersonal Caring, which is also known as the Theory of Human Caring. Watson was born in West Virginia and is currently settled in Colarado (Cara, 2003). She graduated from the University of Colarado and did her Master's degree in psychiatric-mental health nursing (Cara, 2003). She further achieved Ph.D degree in psychology and counseling. She is the founder of the Center for Human Caring located in Colarado and is currently a distinguished professor at the University of Colarado (Cara , 2003). The theory was developed by the nursing scholar based on her experiences in the field of mental health, psychology and counseling. This theory is very important for the nursing profession because it emphasizes the role of humanistic perspective of profession based on

Thursday, October 17, 2019

Case Assign MGNT Strategy Implementation Essay Example | Topics and Well Written Essays - 1250 words

Case Assign MGNT Strategy Implementation - Essay Example The main focus of the company was on eliminating the wastage of time and raw materials at every step of the production process. Due to this reason the company introduced fast and flexible process of manufacturing so that they could supply the customers with the best product on the right time and at an affordable price (Becker, 2012). Toyota improved their production quality by: Implementing a culture of learning within the organization for continuous improvement. Increasing the quality of the working systems. Introducing affordable alternatives for new expensive technology in the market. Creating a perfect business process within the company (ICMR, 2010). Toyota faced different business problems from other automobile companies. The company targeted a small market segment but it had to produce a variety of cars on the same assembly line. The only solution of this problem was to introduce flexible operation. This is when Toyota production system was introduced in the company. They inco rporated the idea of Just-In-time system, inspired by the ideas from American supermarkets. The company also became inspired by the idea of W. Edward Deming, which encouraged Toyota to adopt a systematic approach for solving the problems and this would lead to continuous improvement. This process was called Kaizen (Weemooseus- edublogs, 2010). The main motive of Toyota Production system was to minimize the time spend on activities which are not important or necessary. The major activities in the organization which were non-value adding waste were: Defects Disguise employment Inventory in excess Overproduction Strategic Implementation Factors Strategies are usually formulated by the top level management of the company, but the people responsible for implementing the strategy are different. Implementation is the process that links the top level management with the other employees of the organization. Strategy formulation and implementation of the strategy are two sides of the same coi n. Implementation is a process with the help of which the strategies and the policies of the company are put in action by developing programs, budgets and procedures (Kachru, 2005, p. 391). To see that the strategies have been properly implemented it is important to use the capabilities of a few to check those implementations. The factors such as the structure, culture, people of the organization, commutation, control and the outcome is very important for an organization to successfully implement the strategies. To see that the strategies formulated have been carefully implemented, the organizational structure and culture should be reviewed. In the mid of 2000 Toyota faced number of safety issues in their cars. The most notable problems Toyota faced in its design, development, suppliers, production and maintenance was due to the resignation of a number of talented professionals from Toyota. The 2007 consumer reports did not give any ratings to the cars manufactured by Toyota. The co mpanies had shortage of experts, and maintaining high quality became a million dollar question for Toyota. They had time pressure and lack of resources. The sales went down and the strengths, hybrids and electric cars were not helping the company revive (The Guardian, 2010). Structure The structure affects the organization indirectly. It also affects the implementation of strategies through the flow and control of information. The organization should always align the design and the capabilities

MGT Essay Example | Topics and Well Written Essays - 500 words

MGT - Essay Example He also brought to our notice about Hassan and Khalifa from MGT3710 class. Throughout the conversation all the group member appeared to be very active and motivated to give their best. We decided to have our 1st group meeting in the next class. On 29th January, we had our first meeting in the class at about 11:35 am. We had a new member added to the group. Along with the new member the rest of the group was informed and instructed about the job regarding 3710 class. The group members were asked to advise and supervise the 3710 class but not give them any ideas. Everyone in the group was comfortable with the given information. The groups mission was to collect 1000$ which will ultimately go to the SEED Program. We had two things to be worked upon, 1. To collect about 1000$ which will go to the business school for SEED Program and 2. To make the students of MGT3110 pass the finals. We started discussing amongst each other and brainstorming about different ideas. Many of us came up with unique ideas to be worked upon. As we were sharing and discussing the ideas we also started noting them down on a piece of paper. We started having individual reactions from the group member on each of the noted ideas which was a great help.

Wednesday, October 16, 2019

Theory of Human Caring Essay Example | Topics and Well Written Essays - 1750 words

Theory of Human Caring - Essay Example According to Watson (2009), "nursing is a lifetime journey of caring and healing, seeking to understand and preserve the wholeness of human existence, and to offer compassionate, informed, knowledgeable human caring to society and humankind." Thus, nurses play an important role in the healing of human suffering. In this essay, role of Watson's theory in caring of patients in nursing profession will be discussed through review of a particular case and reflection. Case scenario 55 year James was transferred to the neurology ward from neurosurgical ICU to which he was admitted one week ago with right sided hemiplegia following stroke. Besides right sided hemiplegia, the patient had bladder and bowel incontinence, pneumonia and depression. I was one of the nurses assigned to take care of the patient. The patient stayed in the stroke rehabilitation ward for 4 weeks. During the first week in the ward, I found James to be depressed and frustrated. His only family member with him was his wif e. I found out from the couple that they had 2 sons, who were married and stayed in different countries. They had not come down because the parents did not want to trouble them and hence did not deliver proper information. During my sessions of nursing care I convinced the patient that their sons be asked to come down as it would make the patient feel a lot better. I finally managed to convince them to do so in the second week and when their sons came down, the patient was a lot better psychologically. The patient was a spiritual person and believed in Christianity. He missed attending church regularly. I allowed him to offer prayers by arranging a father to meet him every week. This uplifted the psychological and spiritual morale of the patient. As he improved, I asked his wife and sons to contact a few friends of James and asked them to meet him in the rehabilitation center. James was very much upset about his physical deficiencies because of stroke, especially the bowel and bladd er incontinence. I instilled lot of confidence and hope in the patient and told him that recovery occurs with good positive outlook and physiotherapy. The patient got discharged after 4 weeks. When he came for review after 4 weeks of discharge, he was a lot more improved physically and psychologically and confident person. Jean Watson and her theory Jean Watson, an eminent nurse educator and theorist has contributed significantly to the profession of nursing through her famous theory, the Theory of Transpersonal Caring, which is also known as the Theory of Human Caring. Watson was born in West Virginia and is currently settled in Colarado (Cara, 2003). She graduated from the University of Colarado and did her Master's degree in psychiatric-mental health nursing (Cara, 2003). She further achieved Ph.D degree in psychology and counseling. She is the founder of the Center for Human Caring located in Colarado and is currently a distinguished professor at the University of Colarado (Cara , 2003). The theory was developed by the nursing scholar based on her experiences in the field of mental health, psychology and counseling. This theory is very important for the nursing profession because it emphasizes the role of humanistic perspective of profession based on

MGT Essay Example | Topics and Well Written Essays - 500 words

MGT - Essay Example He also brought to our notice about Hassan and Khalifa from MGT3710 class. Throughout the conversation all the group member appeared to be very active and motivated to give their best. We decided to have our 1st group meeting in the next class. On 29th January, we had our first meeting in the class at about 11:35 am. We had a new member added to the group. Along with the new member the rest of the group was informed and instructed about the job regarding 3710 class. The group members were asked to advise and supervise the 3710 class but not give them any ideas. Everyone in the group was comfortable with the given information. The groups mission was to collect 1000$ which will ultimately go to the SEED Program. We had two things to be worked upon, 1. To collect about 1000$ which will go to the business school for SEED Program and 2. To make the students of MGT3110 pass the finals. We started discussing amongst each other and brainstorming about different ideas. Many of us came up with unique ideas to be worked upon. As we were sharing and discussing the ideas we also started noting them down on a piece of paper. We started having individual reactions from the group member on each of the noted ideas which was a great help.

Tuesday, October 15, 2019

The Trial Film Analysis Essay Example for Free

The Trial Film Analysis Essay Brief Biographical Data of Orson Welles George Orson Welles or popularly known as simply Orson Welles, was a great American director, actor, writer, film, television, stage and radio producer. He also won in the prestigious Academy Awards. Welles became famous through his radio broadcast’s The War of the Worlds. It called a large number of avid listeners to panic. His works such as Macbeth and the contemporary figurative adaptation of Julius Caesar became legends. In 1941, Welles directed, co-wrote, starred and produced the critically acclaimed Citizen Kane. The film, according to polls of many film critics, was the greatest film ever made in film history. However, despite the unquestionable talents and several awards won, the rest of his career was usually hindered by incompetent studio interference, lack of funding and other unfortunate happenings. However, despite these difficulties, his film Othello won the Grand Prix du Festival International du Film at the Cannes Film Festival in 1952. In addition, his Touch of Evil awarded top prize at the Brussels World fair. Anyhow, Welles considered his film Chimes at Midnight and The Trial to be his best works ever. The Trial The Trial is a film that is even more visually extravagant than Orson Welles’ previous films. He used several themes, symbols and filmic devices that had become his trademarks. Depth of field photography, low-angle shooting, elaborate frame composition, visibility of constructed ceilings in the frame, attention to sound editing, expressionistic lighting, gigantic statues, houses in ruins are just some on the themes and filming techniques that Welles employed. The movie opened with animated pin-screen illustration of the parable of the law of Alexander and Claire Parker. Welles dubbed the voice who also played as K.’s advocate. He also dubbed all the authority figures’ voices. The parable is about a man who seeks admission to the Law but rather denied by the guard and thus waited until he can enter. With the film opening with the parable, it positioned the audience in an opportunity position from which to judge the character’s actions since they are certainly refracted through and thus rendered meaningful illustrations of the parable. Kafka’s tale absurdity is somehow interceded by the visual explanation given in advance. The film also raised but did not explore too much the most radical implication of its premise, in which sin, guilt and responsibility are not forced on any man. Demonstrated by the opening parable, the admittance to the law is not closed rather it is man who prevents himself from entering because of the notion of sin, guilt and responsibility that conceived of closing the door. Use of Principles of Design The film opened with a parable and in this opening, Welles executed the used of the designs, such as the unity, repetition and balance very well. The simple illustration of the doors created unity that somehow gave a sense of harmony and unity that pulls the whole picture or story together. The principle of direction and emphasis was also used effectively because we can immediately see the focus of a certain scene that Welles wanted us to see first. I can say that what twined the different episodes is Welles’ vision of the different settings as interconnected through a series of secret dark passages, entrances, staircases and exits that disintegrate the distinction between the private and public spaces. Welles explained in his 1965 interview that his â€Å"original design was to have the number of realistic elements gradually diminish and the number of realistic elements gradually disappear until what remains open is the spaces and as though everything has dissolved.† If compared to the 1993 adaptation of The Trial directed by David Hugh Jones and starred by Kyle MacLachlan, in my opinion, was beautiful and a subtle exploration of Kafka’s masterpiece nuances but still, an ordinary adaptation of the old one. Nevertheless, when it comes to the principles of design, of course, Jones’ adaptation will top the score. Colors, of course add spice and life to the design. The principles of design applied were definitely new and more appealing than the old version of Welles. However, Welles’ The Trial, has its own character and seemed to stand the time and have an eternal presence in each scene. I can also say that it is indeed easier to do an independent film when art and designs are at stakes and better results when you are the one with full control. Despite the lack of funds because of the low commercial value, a film will be outstanding when it comes to the employment of designs, arts, and every element useful for a successful film. Welles’ baroques set design and intelligent use of the principles of design also enhanced the impression that the different settings served as a â€Å"symbolic, nightmarish manifestations of K.’s inner turmoil† and dissipate the absurdity of Kafkaesque, in which straddled the line between the illogical and logical, the unreal and real. I can say that the film, then, is more of an allegory than a novel. Therefore, I can say that Welles was indeed successful in using the principles of design, however limited his budgets and resources were. References: Charles Higham, The Films of Orson Welles, University of California Press, Berkeley, 1970. Albert Camus, â€Å"Hope and the Absurd in the Work of Franz Kafka†, The Myth of Sisyphus and Other Essays, trans. Justin O’Brien, Vintage Books, New York, 1955. Principles of Designs Tips. Life Tips, 2008. http://graphicdesign.lifetips.com/cat/55144/ principles-of-design/index.html. Retrieved, September 9, 2008.

Monday, October 14, 2019

Polymers and its applications

Polymers and its applications ACKNOWLEDGEMENT I take this opportunity to present my votes of thanks to all those guidepost who really acted as lightening pillars to enlighten our way throughout this project that has led to successful and satisfactory completion of this study. We are really grateful to our HOD for providing us with an opportunity to undertake this project in this university and providing us with all the facilities. We are highly thankful to Mr. Harminder Singh for his active support, valuable time and advice, whole-hearted guidance, sincere cooperation and pains-taking involvement during the study and in completing the assignment of preparing the said project within the time stipulated. Lastly, We are thankful to all those, particularly the various friends who have been instrumental in creating proper, healthy and conductive environment and including new and fresh innovative ideas for us during the project, their help, it would have been extremely difficult for us to prepare the project in a time bound framework HISTORY:- Polymers were discovered long before anyone understood what they were. It wasnt until 1920 that German chemist Hermann Staudinger (1881-1965) made his macromolecular hypothesis, suggesting that polymers are actually giant molecules formed by the permanent attachment of countless smaller molecules. INTRODUCTION:- A polymer is a large MOLECULE composed of repeating structural typically connected by chemical bonds like covalent bonds. Polymers are composed of very high molecular masses formed by the combination of large number of simple molecules. GEOMETRY:- Polymers (or macromolecules) are very large molecules made up of smaller units called monomers or repeating units, covalently bonded together. Monomers / Repeat Units The identity of the monomer residues (repeat units) comprising a polymer is its first and most important attribute. Microstructure:- The microstructure of a polymer (sometimes called configuration) relates to the physical arrangement of monomer (which I have explained above) residues along the backbone of the chain. CLASSIFICATION OF POLYMERS:- On the basis of structure- LINEAR POLYMERS BRANCHED POLYMERS CROSS-LINKED POLYMERS On the basis of molecular forces Elastomers Fibers Thermoplastics Thermosetting polymers Thermoplasts: These are the polymers which can be easily softened repeatedly when heated and hardened when cooled with little change in their properties. When heated due to the absence of cross links, they become free to move and and can be moulded into any desired shapes. EXAMPLES- Polyvinyl Chloride (PVC) and Polystyrene and Polymethyl methacrylate Thermosets:- These are the polymers which undergo permanent change on heating and can not be remoulded into our desired shape. On heating their cross links get highly linked with each other and becomes hard and infusible. EXAMPLES-Bakelite,formaldehyde etc. PROPERTIES:- Tensile strength Higher tensile strength holds a greater weight before snapping. Tensile strength increases with polymer chain length and crosslinking of polymer chains. Melting point The term melting point when applied to polymers, suggests not a solid-liquid phase transition but a transition from a crystalline or semi-crystalline phase to a solid amorphous phase. Boiling point The boiling point of a polymeric material is strongly dependent on chain length. The polymers with a large degree of polymerization do not exhibit a boiling point because they are decomposed before reaching their respective theoretical boiling point. FUN FACT: The polymer inside disposable diapers is called sodium polyacrylate. It can instantly absorb about 800 times its mass in water. APPLICATIONS OF POLYMERS:- Molecular science has developed enormously in recent eras. Molecular science has a major role in our lives. It has become a necessity in our daily routines we shall talk now about the basic applications of polymers without which life wasnt that easy. We are going to discuss some of the main polymers used in our lives. RUBBER:- HISTORY OF RUBBER: Natural rubber, obtained from the sap of the hevea tree. Rubber was named by the chemist Joseph Priestley who found that a piece of solidified latex gum was good for rubbing out pencil marks on paper. TWO TYPES OF RUBBER ARE THERE:- NATURAL RUBBER VULCANIZED RUBBER (SYNTHETIC RUBBER) NATURAL RUBBER:- Natural rubber is a polymer of isoprene (2-methyl-1, 3-butadiene), with a joined network structure.There is no cross links between the polymer chains. It is not hard and tough. It becomes sticky and soft when heated. It can be easily deformed but regains its original shape after the stress is released. It involves a addition reaction in which one double bond in isoprene open to form a new bond with next unit forming a large chain. VULCANIZED RUBBER:-. A chemical reaction of sulfur (or other vulcanizing agent) with rubber or plastic to cause cross-linking of the polymer chains; it increases strength and resiliency of the polymer chemically; the process involves the formation of cross-linkages between the polymer chains of the rubbers molecules. It was invented by Charles Goodyear in 1839.The formation of cross links formed at the time of vulcanization at the reactive sites makes rubber hard, tough with greater tensile strength. It has very high elasticity, resistance to oxidation and organic solvents. The sulphur bridge in this figure prevents the slip of the chains and rubber can be stretched to a limited extent and when tension is removed the chains try to coil up regain its original shape. OTHER TYPES OF RUBBER:- NEOPRENE RUBBER:- USES: used as insulator, making conveyor belts, printer roller belts are also made from it. SBR (Styrene Butadiene Rubber):-Known as BUNA-S USES: it is used for making automobile tyres and footwears. NITRILE RUBBER:- Recognized as BUNA-N USES:-it is used for making oil seals, manufacture of hoses and tank linkings. REACTIONS INVOLVING IN THERE FORMATIONS:- PLASTICS OR POLYHALO-OLEFINS:- A very useful but common commodity of our life. But nowadays it has become a serious problem due to its problem of degradation which is a process which is a time consuming process. These are called polyhalo-olefins because they are derived from halogen substituted olefins. POLYVINYLCHLORIDE-(PVC):- Its monomer is unit is vinyl chloride. it is prepared by heating vinyl chloride in an inert solvent in the presence of peroxides (eg.dibenzoyl peroxides).It isa hard horny material. It is a thermoplastic polymer and its plasticity can be increased . Fig 15.0 USES:- It is used in manufacturing of rain coats, hand bags, curtain clothes, toys Artificial flooring. As a good insulating material in wires and other electrical goods. For making gramophone records. TEFLON:-(POLYTETRAFLOUROETHYLENE): Tough material resistant to heat and chemical actions such as acids and bases. It is an addition polymer of tetraflouroethylene.It is bad conductor of heat. USES: It is used as a material resistant to heat and chemical attack in household works. For coating articles and cookware to make them non-sticky as non stick utensils For making gaskets, pump packaging, valve, seals, non-lubricated bearings, etc. POLYESTERS:- Fibers represent a very important application of polymeric materials, including many examples from the categories of plastics and elastomers.It involves ester linkages TYPES OF POLYESTERS(FIBRES):- TERYLINE:-It is a polymer of ethylene glycol and terephthalic acid. Also known as Dacron. USES:- For making cloth by mixing with cotton. For making magnetic recording tapes. NYLON66:-Monomers are hexamethylenediamine and adipic acid. USES:- Used for making bristles of brushes. In textiles and also for making sheets. It is blended with wool to make socks and sweaters. NYLON 6:- its monomer is caprolactum made up of cyclohexane. USES:- It is used in the manufacture of tyre ,cords, fabrics, and ropes. CONCLUSION:- We have tried to give a brief information on polymers .Polymers are everywhere around us and we tried to show a glimpse of polymers applications which are commonly used in our lives like plastics nylon and day to day used commodities. MATERIAL AND FIGURE REFRENCES:- http://www.plastiquarian.com/top.htm http://www.csua.berkely.edu/~ranga/school/me223/nylon.gif http://www.openlearn.open.ac.uk/course/view.php?id=2937 http://www.britanica.com/EBchecked/topic/468696/polymer http://www.polymertalk.com/history_of_polymers.php http://en.wikipedia.org/wiki/silicone http://en.wikipedia.org/wiki/branching_%28chemistry%29 http://www.polymertalk.com/classification_of_polymers.php http://docs.google.com/viewer?a=vq=cache:Wbn5XOJDt:www.cmse.ed.ac.uk/MSE3/Topics/MSE3-polymers.pdf+intoduction+of+polymershl=engl=insig=AHIEtbQ22RNSIoIyoXUP9HtDd-nakz-w http://www.cem.msu.edu/~reusch/VirtualText/polymers.htm

Sunday, October 13, 2019

Metropolis Symphony Essay -- Music Musical Musician Papers

The Development of the Programmatic Symphony from the 19th Century into the 21st Century Since the early symphonies of Sammartini and Stamitz the orchestral symphony has underwent constant development. In the early nineteenth century Beethoven started a new form of the symphony when he composed a symphony based on programmatic music. The programmatic symphony is a composition that is written with non-musical influences. "Program music is instrumental music which tells a story illustrates literary ideas, or evokes pictorial scenes. Though the term originated with Listz, illustrative music has existed for as long as music itself."(Kennedy p. 579) The form is more like a multi-movement tone poem that tells a story though music. The symphonies of Haydn, and Mozart were pieces written with music that was not influenced by non-musical ideas. Other symphonies that have been written that are programmatic are Symphonie Fantastique by Berlioz, Symphony no. 3 "Pastoral" by Vaughan Williams, and Metropolis Symphony by Michael Daugherty. This paper will show the similarities and differences between the programmatic symphonies of Beethoven, Berlioz, and Daugherty. Ludwig Van Beethoven 1770-1827 The first major programmatic symphony was written by Ludwig Van Beethoven in 1807-08. Although it was not completed until 1808 there are sketches for the symphony that go as far back as 1803. This was his sixth symphony and it was in F major. The first performance of the symphony was on December 22, 1808 which was the same premier of his fifth symphony. This symphony has five movements. The instrumentation for the symphony includes two flutes and piccolo, two oboes, two clarinets, two bassoons, two horns, two ... ...also has expanded the size of the wind section of the orchestra with several more instruments. While Beethoven and Berlioz composed their symphonies as complete works Daugherty allows conductors to perform movements separately if they desire. This makes each movement more like a tone poem than a full symphony. It is easy to see though by the Dies Irae in the fifth movement and the storm like atmosphere of the fourth movement how Daugherty was influenced by these two composers who came over one hundred years before him. In conclusion, the programmatic symphony has been used to create some of the greatest works of musical literature in the past two hundred years. In the next century composers will probably follow in these composers’ footsteps and expand the size of the orchestra to create new timbres and tell stories through tone painting in symphonies.

Saturday, October 12, 2019

Definitions of Words Relating to Colonial America :: American History Puritans War Essays

Definitions of Words Relating to Colonial America 1.Iroquois Confederacy— confederation of five indigenous North American peoples, or nations, Mohawk, Oneida, Onondaga, Cayuga, and Seneca; founded c.1570. 2.Powhatan Confederacy— a group of 30 Native American tribes of the Eastern Woodlands. 3.Raleigh, Sir Walter— 1554-1618, English soldier, explorer, courtier, and man of letters. He conceived and organized the colonizing expeditions to America that ended tragically with the lost colony on Roanoke Island, VA with Christopher Marlowe and George Chapman. 4.Roanoke Island— 12 mi (19 km) long and 3 mi (4.8 km) wide, off the NE coast of North Carolina between Albemarle and Pimlico sounds, site of the earliest English colony in North America. The first colonists, sent out by Sir Walter Raleigh landed in Aug. 1585 but returned to England in 1586. A second group, arriving in 1587, disappeared by the time additional supplies were brought from England in 1591. Artifacts from the lost colony are displayed in Fort Raleigh National Historic Site on the island. 5.Virginia Company— name of two English colonization companies chartered by King James I in 1606. One founded on the Plymouth Colony; the other, latter known as the London Company, founded colonies in the South, notably Jamestown, VA. 6.Jamestown— former village, SE Va., first permanent English settlement in America; est. May 14, 1607, by the London Company on a peninsula (now an island) in the James R.; named for the reigning English king, James I. 7.Royal Colony— In 1691 a new royal charter was granted for the colony of Massachusetts, which incorporated the Massachusetts Bay Colony, Plymouth, Martha's Vineyard, Nantucket Island, Maine, and Nova Scotia. Under the charter a popular assembly was established to aid the royal governor, and the right to elect representatives to the assembly was based on property qualifications, rather than on church membership. The royal charter ended control of Massachusetts government by Puritan religious leaders. 8.Puritans— ‘Followers' of Puritanism, a movement for reform in the Church of England that had a profound influence on the social, political, ethical, and theological ideas in England and America. In America the early New England settlements were Puritan in origin and theocratic in nature. The spirit of Puritanism long persisted there, and the idea of congregational democratic government was carried into the political life of the state as one source of modern democracy. 9.Plymouth Colony— settled by the Pilgrims in Massachusetts in 1620. The settlers had difficulty surviving early hardships, although a treaty with neighboring tribes assured peace for 50 years.

Friday, October 11, 2019

My Conflict Management Philosophy Essay

There are always times when one doesn’t agree with another opinions and decisions. Thus, conflict occurred. I’m pretty sure everyone faced conflict almost every single day in their life and it’s inevitable. However there are few ways to solve it or even simplify the problem. I can still recall I faced a huge conflict with my mom few years back. I am vexed whether to continue my studies in university or college. I went to do a lot of research and seek for counselor’s opinion. My counselor teacher is the only person which I can trust the most as she has helped me a lot during my high school years. Despite that, she also taught me ways to release stress as well. She is also willing to give me extra tuition classes to help me in my studies. That is why I’ll always put more efforts and be diligent to achieve a good result. Thus to me, she is the most respectful teacher in my life. Of course when I have no idea what course to further my study, I will look for her and seek her advices. She is indeed a very good and kind teacher. She helped me in differentiating the advantages and disadvantages of the university and college that finally conclude first problem. I found my passion in studying Mass Communication and so far Han Chiang College is one of the famous in teaching Mass Communication course in Penang. Hence, I make my decision to study there. However, things did not go on smoothly. I have a serious argument with my mom as I told her I will further my studies in Han Chiang because she wanted me to continue my studies in a university. All along my mom is a stubborn person. She will never listen to the others opinion except for my dad. It is certainly not easy to persuade my mom. My mom will always use the method of forcing to make me follow her way and every time I obey to her decision. However for the sake of my own future, I did not follow her way this time. My mother is indeed an indomitable person. She was so angry that time that she wants to kick me out of the house. Based on this situation, firstly I practiced the method of withdrawal because I know if I continue to argue with my mother, it’s going to be another endless fight. No matter how long we quarrel for it, it will also not come out with any solution. Then I just shouted to her to end our argument on that day. After that, I quickly walk back to my bedroom and shut my door. My mom was very angry of me that time because I simply throw my temper on her. Consequently, our relationship became worsen and my mom did not talk to me for several days. During that time, I am very disappointed and yet sad. I’m disappointed because my mom forces me to follow her way and do something that I don’t wish to. I’m sad is because of relationship with my mom is getting worse and worse. After calming myself down, I know this topic is unavoidable. Thus, I come out with a solution to solve it. I know the only person who can help me to solve this problem is my dad. So I went to look for my dad and discuss it with him. I used the method of negotiating to discuss with my dad. I told him I love my mom and I don’t want her to upset but I really don’t want to force myself to do anything that I don’t like. After having a talk with my dad, he told me that he will talk to my mum and discuss it with her. After that, my dad helps me to persuade my mom. Lastly, my mom allows me to continue my studies in Han Chiang College but with a condition. My mom doesn’t want me to study in college because she is afraid I’ll pay much attention on my studies as college schedule is much more flexible than in university. Thus, she’s afraid that I’ll skip my classed very often and hang out with friends. So, I made a promise to her that I’ll not skip my classes and I’ll try to maintain my CGPA above 3. 0 for every semester. In conclusion, we used the method of compromising in this mater.

Thursday, October 10, 2019

Analysis of General Environment Essay

HSBC Bank (China) is one of the first foreign banks to incorporate locally in mainland. As a foreign-owned bank, HSBC has the largest services network among foreign banks, targeting the middle-class individuals and business-oriented individuals in China. With the globalization, China is seen as the biggest market in the world. The general environment will bring great effect to the future development of the HSBC (China). The specific analysis is as follow. 1. Demographic Environment China has the largest population in the globe that the number has already reached 1.4 billion. Most of the people are living in the east and middle areas. In other words, the middle and above-middle-class people assemble in these two areas with the demand of bank service. (National Bureau of Statistic of China, 2011) As the societal pressure growing heavier, less people are willing to give birth to baby so that the problem of population aging arises. According to the reform and opening policies, the east and south areas are better developed than the central and the west. People in the coastal region have higher average income than others. As a result, HSBC (China) mostly build its banking network in the east and south areas, which are so called first-tier cities. Meanwhile, it has also expanded branches in some second-tier cities in the central area of China. 2. Economic Environment As an emerging market, China is developing at a very fast speed with continually growing Gross Domestic Product as well as high export surplus. However, in terms of global environment, the world still not recovers from the economic recession. The financial market in mainland has been impacted that the exchange rate of RMB has gone higher and higher, which has been result in the inflation. To better control the financial market, the interest rate has been increased to limit the cash flow in the market and personal saving rate goes up that people are encouraged to save money in banks rather than investing. Another economic factor putting effect on HBCS in China is the unemployment rate. China government devotes into keeping the unemployment rate low and stable, because once the rate rises sharply, this will destroy the harmony of the society. Consequently, HSBC (China) should take this factor into account to obtain trust and support from the local government. 3. Political Environment In China, banks are supervised by the China Banking Regulatory Commission. There are many barriers setting in front of those foreign banks in China, such as foreign banks are not permitted to establish a business of any scale in the mainland, since the Chinese legislations limit on how many local banking operations can lean on foreign banks. On the other hand, the new parties have held the power, which means new policies and new reform may come into being. Different policies and reform will significantly affect the existence of HSBC in China. With the improvement of the capital market, the financial environment will be deregulated and gain a more loosening environment. Moreover, foreign banks in China have to be charged tax, which will increase the cost and lower the profits of HSBC in mainland. As the compulsory education popularizing, more and more people think highly of the banking service. They become to have good knowledge to the banking items and are tied closely to those services. 4. Socio-cultural Environment Banks serve for people’s demand and need. People’s attitude towards banks is influenced by the social-cultural environment. In China, customers are more conservative that they prefer saving money. Therefore, more emphasis should be put on the retail banking services in mainland. Recent years, with the impact of financial crisis, people are less trusting banks. Banks are seen as greedy organizations by the public, which was result from arbitrary banking charges. 5. Technological Environment Technological change can bring new style of business to organizations. It can change both the product and business way. Since the constant improvement of the Internet, HSBC has launched its online banking services in China. People can have an electronic account to check user’s balances and transactions, make transfer as well as pay bills. Simultaneously, doing business through the Internet not only save the time for customers, but also simplify the business process for HSBC so that they can cut large amount of cost. Furthermore, the development of the mobile phone also benefits the banking services. People can easily access to their account through the mobile Internet. Secondly, particular applications have been invented for mobile users to manipulate their banking service. For example, HSBC has its own applications which can be used for IOS (iphone) and Android operating systems. These applications are convenient to use and also help HSBC to saving labor as well as time cost. 6. Global Environment The global environment is somewhat cannot be controlled by the organizations itself. The global economy stays in a recession for a period of time and seems to be difficult to recover from it. The subsequent influences of the financial crisis affect the economy in China. HSBC (China) has earned less profit these years. Although the macro environment is not so optimistic, China is still the hugest potential market around the world. Besides China, there are still many emerging countries appear in the world, like India. In the future, HSBC (China) should pay attention to create more advantage competitiveness than those HSBC banks in other international regions. Reference Eternity in an hour. (2009). Environmental Analysis-HSBC(A Marketing Perspective). Available from: http://cloudchronicler.net/2009/10/14/environmental-analysis-hsbc-draft-copy/ HSBC Bank (China) Company Limited Fact Sheet. (2013). Available from: http://www.hsbc.com.cn/1/PA_1_083Q9FFKG80E20RA9Q00000000/content/china/about/docs/factsheeten.pdf HSBC Bank (China). (2013). About HSBC (China). Available from: http://www.hsbc.com.cn/1/2/hsbc-china-cn Sina News. (2012). The War of the Interest Rate. Available from: http://news.dichan.sina.com.cn/2012/08/02/539030.html Studymode. (2012). A PEST Analysis Report of HSBC. Available from: http://www.studymode.com/essays/Pest-Analysis-Hsbc-Holding-Plc-1206636.html The Wall Street Journal. (2011). In China, Foreign Banks Still Lag Behind. Available from:http://online.wsj.com/article/SB10001424053111904491704576574281790473152.html